QX - 314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV

نویسندگان

  • Mackenzie E. Hofmann
  • Tally M. Largent-Milnes
  • Jessica A. Fawley
  • Michael C. Andresen
چکیده

External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1 1 2 Mackenzie E. Hofmann, Tally M. Largent-Milnes*, Jessica A. Fawley, and Michael C. Andresen 3 Department of Physiology & Pharmacology 4 Oregon Health & Science University 5 Portland OR, USA 6 7 8 9 10 Running Title: QX-314 non-selectively inhibits afferent conduction 11 12 To whom correspondence should be sent: 13 Dr. Mackenzie E. Hofmann 14 Department of Physiology and Pharmacology 15 Oregon Health & Science University 16 Portland, Oregon 97239-3098 17 E-mail: [email protected] 18 Voice: (503) 494-5831 19 FAX: (503) 494-4352 20 21 22 *Current address: University of Arizona 23 Department of Pharmacology 24 1501 N. Campbell Ave. 25 LSN 647 26 Tucson, AZ 85724-5050 27 28 29 Conflicts of Interest: None. 30 31 32 Acknowledgements: This work was supported by grants from the National Institutes of Health, R01-HL33 105703 (MCA) F32-DE-022499 (TML-M) and F32 HL112419 (MEH). The content is solely the 34 responsibility of the authors and does not necessarily represent the official views of the National Heart, 35 Lung and Blood Institute or the NIH. 36 37 Articles in PresS. J Neurophysiol (September 3, 2014). doi:10.1152/jn.00316.2014

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تاریخ انتشار 2014